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OTHER SERVICES: Paternal & Maternal Lineage Y-STR MALE LINEAGE TESTING Male   Lineage,   or   Y-STR,   testing   is   a   DNA   test   that   specifically   looks   at   the   Y   chromosome, which   is   present   only   in   males.   These   tests   are   useful   in   determining   relatedness   through   male lineage, although they are often more useful in disproving a relationship. If    attempting    to    determine    if    male    participants    come    from    the    same    paternal    lineage,    the participants   must   share   or   suspect   that   they   share   a   relative   from   whom   they’ve   descended   along the same line of males. For   instance,   if   attempting   to   determine   if   potential   male   cousins   are   true   cousins,   their   fathers must   be   brothers   who   shared   the   same   father.   If   the   male   lineage   descends   from   the   same   male ancestor,   the   Y   chromosome   profile   obtained   through   the   test   will   be   identical   (mutations   may occur)   between   the   two   potential   male   cousins,   proving   that   they   likely   come   from   the   same   male lineage.   If   the   participants   do   not   have   the   same   Y   chromosome   profile,   they   do   not   come   from the same male lineage. While   Y-STR   testing   is   a   useful   tool   to   examine   male   lineage,   this   testing   does   not   determine   the specific   relationship   between   two   males   within   the   same   male   lineage.   Despite   this,   Y-STR testing   can   exclude    males   from   a   male   lineage,   and   that   can   often   be   important   information.   For example,   if   an   alleged   father   is   not   available   for   testing   with   a   male   child,   you   may   use   the alleged   father’s   brother   (must   be   descended   from   the   same   father)   or   alleged   father’s   father.   If   the alleged   uncle   or   paternal   grandfather’s   Y-STR   profile   does   not   match   the   child,   the   alleged   father is most likely not the biological father. Y-STR   testing   is   also   frequently   used   on   samples   where   you   are   looking   for   male   DNA   but   there may   be   a   lot   of   female   DNA   present   (e.g.   female   underwear   samples).   In   infidelity   cases,   where an    individual    may    be    looking    to    see    if    another    male’s    DNA    is    present,    Y-STR    is    a    good alternative   to   regular   STR   testing   because   it   amplifies   and   examines   ONLY   male   DNA,   which can often be hard to detect in female underwear. If   you   are   attempting   to   pursue   a   Y-STR   DNA   test,   please   contact   GenQuest   to   discuss   your situation and how to proceed. MITOCHONDRIAL FEMALE LINEAGE TESTING GenQuest   now   offers   mitochondrial   DNA   testing!   Mitochondrial   (mtDNA)   tests   are   used   to determine   relatedness   through   female   lineage   to   help   discover   maternally-linked   relationships. Unlike   male   lineage   tests,   participants   in   mtDNA   tests   can   be   male   or   female   who   suspect   they share a relative through a maternal line. Mitochondrial   DNA   is   passed   on   to   children   of   both   sexes   through   the   mother.   In   a   mtDNA comparison,   analysts   look   at   the   mtDNA   sequence   of   each   participant   side   by   side   and   if   certain regions   along   the   sequence   are   shared,   this   indicates   that   the   participants   share   a   common   female ancestor through their maternal heritage, such as a mother or maternal grandmother. Like   male   lineage   testing,   mtDNA   tests   do   not   determine   the   specific   relationship   between participants,   but   only   proves   that   they   do   or   do   not   share   a   female   ancestor   along   the   maternal line. Difference between Lineage Testing and Ancestry Testing Ancestry    testing    (not    available    through    GenQuest)    traces    your    DNA    back    through    several thousands   of   years   to   determine   racial   heritage   and   potential   relatives   in   the   company’s   ancestry system.   Paternal   and   Maternal   comparisons   are   ways   to   confirm   much   more   recent   relationships in   your   male   or   female   lineage.   Often   if   ancestry   testing   identifies   potential   relatives,   those findings   can   be   confirmed   with   Y-STR   or   mtDNA   testing.   Visit   our   Interpreting   Your   Results   page for details on how to interpret your Y-STR testing results.
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The secret to everything is in your DNA

Genetics · Paternity · Immigration · Forensics
Call Toll Free (877) 362-5227
Lineage Testing MALE LINEAGE  Male   lineage,   or   Y-STR   testing,   is   a   DNA   test   that specifically    looks    at    the    Y    chromosome,    which    is present    only    in    males.    These    tests    are    useful    in determining     relatedness     through     male     lineage, although they   are   often   more   useful   in   disproving   a relationship. If   attempting   to   determine   if   the   participants   come from   the   same   male   lineage,   the   participants   must share    or    suspect    that    they    share    a    relative    from whom    they’ve    descended    along    the    same    line    of males. If   the   male   lineage   descends   from   the   same   male ancestor,     the     Y     chromosome     profile     obtained through    the    test    will    be    identical    (mutations    may occur)   between   two   potential   relatives,   proving   that they   likely   come   from   the   same   male   lineage.   If   the participants   do   not   have   the   same   Y   chromosome profile,    they    do    not    come    from    the    same    male lineage. While   Y-STR   testing   is   a   useful   tool   to   examine   male lineage,   this   testing   does   not   determine   the   specific relationship    between    two    males    within    the    same male   lineage.   Despite   this,   Y-STR   testing   can   exclude   males   from   a   male   lineage,   and   that   can   often   be important information. If   you   are   attempting   to   pursue   a   Y-STR   DNA   test, please   contact   GenQuest   to   discuss   your   situation and how to proceed. Difference    between    Male    Lineage    Testing and Ancestry Testing Ancestry   testing   (not   available   through   GenQuest) traces   your   DNA   back   through   several   thousands   of years    to    determine    racial    heritage    and    potential relatives   in   the   company’s   ancestry   system.   Y-STR comparison   is   a   way   to   confirm   much   more   recent relationships   in   your   male   lineage.   Often   if   ancestry testing    identifies    potential    male-to-male    relatives, those   findings   can   be   confirmed   with   Y-STR   testing. Visit   our   Interpreting   Your   Results    page   for   details on how to interpret your Y-STR testing results.